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Is imatinib generic? In February 2016, a generic version of imatinib (Gleevec), the groundbreaking tyrosine kinase inhibitor, was made available in the United States. Although approved for only a handful of rare diseases, including chronic myelogenous leukemia and GI stromal tumor (GIST), imatinib generated $4.7 billion in 2015 alone.
Why is it called Philadelphia chromosome? Philadelphia chromosome is the first tumor-specific chromosomal change discovered by Nowell and Hungerford in 1960. It was named after the city in which it was discovered. It is a shortened chromosome 22 resulting from a reciprocal translocation of parts of chromosomes 22 and 9.
Do nurse practitioners or physician assistants make more? Both nurse practitioners and physician assistants are mid-level practitioners. They are not doctors, but they take on some roles traditionally taken on by doctors, including making diagnoses and prescribing medication. The PA tradition draws more from a medical model.
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